FTIR Solid State Interaction of Moxifloxacine With Metals
DOI:
https://doi.org/10.46881/ajsn.v1i1.17Keywords:
Quinolones, Moxifloxacin, Carbonyl groups, Metals ions, bidentate, polydentateAbstract
In this research, metal salts containing K+, Zn2+, Cu2+ and Al3+, were used to study the interaction of metal ions with moxifloxacin HCl using Solid state synthesis. The result obtained using Fourier Transform Infrared Spectra, showed a perturbation of the absorption band of the carbonyl groups at around 1700cm-1 in Moxifloxacin HCl when it was triturated in solid state synthesis with Zn2+,Cu2+ and Al3+,indicating an interaction with these metal ions. This interaction was however absent in K+ because the peak was evident at 1708.2 cm.-These interactions may have an effect on therapeutic outcome of co-administration of moxifloxacin HCl with antacids or agents containing metal ions.References
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